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Process development
and optimization
Safety assessment
Automatic batch reactions
Small reactor volume, 10 180 ml, still with the full capability of
all necessary requirements.
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Reactor size is of utmost importance for many reasons. Operator safety,
material consumption, material disposal, experiment time and experiment
cost to mention a few.
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Safety issues when performing close to run-away reactions can always be
controlled and handled better with a smaller reactor than with
a larger.
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Consumption of initial raw materials is less for CPA202/102. This is important
especially in the drug industry where many, and sometimes expensive
as well as hazardous, substances are tested and eventually should
be disposed of.
True results on-line in real time.
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Reduced experimental time for the CPA202. Three to four times faster than
traditional heat-flow
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Higher experiment throughput and lower experiment cost.
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CPA202 presents heat transfer values continuously. Traditional calorimetry
only at selected points of calibration
Factory calibrated reactor in the CPA202, once and for all.
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Traditional calorimetry needs calibration before, during and after each
individual experiment.
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Data from the CPA202 are true and objective, not the result of personal.
Precise reflux operation.
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True measurement of the condenser power, on-line.
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The CPA202 measures the True Heat Flow during boiling. This offers the
possibility to present the power from the chemical reaction during
reflux directly in true power units, on-line. Traditional calorimetry
offers at best operator initiated reflux settings with experiment
specific calibration points. Cumbersome and imprecise!
Capability for various auxiliary probes - IR, Raman, etc.
Handle all types of dosing and sampling, even dosing of dry powder materials
under pressure, which is absolutely unique.
Efficient mechanical stirring with different stirrer shapes, baffles,
baskets, etc.
Stirrer torque is measured inside the reactor
on-line.
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The precise value indicates viscosity changes, fouling, precipitation etc.
all vital for safety judgements during scaling up.
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Traditional calorimetry is equipped with an external torque transducer,
which does not compensate for shaft friction changes. Consequently
the data is less reliable.
Powerful emergency cooling with an internal cooling coil.
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Combined with a smaller reactor volume, the concept is much superior to
the traditional calorimetry. |